In this article, the FEM 3D numerical simulation is built to analyze the internal forces and deformations of piles, with a shieldbore tunnel crossing adjacent to piles of highspeed railway bridge. The results show that piles move deviate from the tunnel in horizontal direction after the tunneling in moderately weathered argillaceous siltstone. The piles’ maximal horizontal displacement is 0.24 mm, the greatest settlement of pile cap’s centre is 0.52 mm, the largest additional internal axial force of piles is 230 kN. As both the deformation and bearing capacity of the piles could meet the specification requirements, no active reinforcement is conducted. The paper proposed the precautions and safety measures when the shield tunnel conducted closely under the pile of highspeed railway bridge based on the previous tunneling experiment. Besides, the rationality of the simulation is demonstrated by the accordance between the computed result and practical monitoring data.