The traditional disease inspection method for highway tunnel structure by using manual inspection by lifting platform is low efficient and will affect the traffic. Hence, the rapid inspection equipment, focuses on tunnel structure and appearance is adopted. It can collect the surface image data of the tunnel rapidly, and the structural disease characteristics can be analyzed by postprocessing software. Five rapid inspection equipments and their application effects are compared to field survey and data collected. Some conclusions are drawn as follows: 1) The result images of the rapid inspection equipment by different manufacturers vary much; and the definition and resolution of single photograph and layout plan of key results are still need to be improved. 2) The manual inspection method can not yet be replaced by rapid inspection method; and the tunnel structure diseases and maintenance measures can be accurately evaluated and determined by considering both two methods effectively. 3) During the management, construction and design of highway tunnel, a favorable disease inspection environment should be considered.