The running cost of machinery shift, varies with construction shift numbers, should be controlled during TBM remanufacturing. Hence, a mathematical relationship model between the running cost and the number of TBM construction shift is established by analyzing the running cost data of TB880E fullface rock boring machine used in Xikang Tunnel of Qinling Mountains, so as to provide theoretical support for the cost management of related enterprises. And then the functional relationship between TBM construction machinery shift and shift number is refined. Finally, by considering the influence of cost during TBM stop and local remanufacturing on construction shift number, the feasibility of the model and functional relationship are verified by TBM running cost of Zhongtianshan Tunnel. It is concluded that the running cost of TBM construction machinery shift is functionally related to construction shift number; and the results can provide reference for budget preparation and cost control of similar tunnel projects and quota determination and refined management of TBM tunnel for relevant managers.