The Xinping Tunnel on Yuxi-Mohan Railway is located in the fault and fracture zone with complex geological conditions. During the construction process, mud and water gushing occur frequently, which are rare around the world. Hence, in order to ensure the successful implementation of the tunnel, key construction technologies for the tunnel crossing fault and fracture zone are obtained in terms of tunnel design and construction, research and discussion, scheme comparison and optimization, field experiment and difficulty treatment. The obtained technologies include advance prediction, advance pre-reinforcement, soft rock large deformation control, one-time excavation with invert, and nonexplosive excavation.