Based on several years’ working practice and experience in highway tunnel design and construction, the authors summarize and compare the security and applicability of several protection measures of lowvoltage distribution system as well as the remaining problems and solutions in highway tunnel. Moreover, they put forward their own view about the selection of protection measures according to the analysis and discussion on the highway tunnel environment and lowvoltage distribution system characteristics. This paper has some practical significance for the future protection measures selection of lowvoltage distribution system in highway tunnel as well as the enhancement of system security and applicability.