The research region of DezhouShangqiu highway in Fan County is located in the Yellow River flooded area, where earthquakes are frequently active and the ground develops with saturated silt and fine sand beds. According to the Code for Seismic Design of Buildings (GB 500112001, Chinese code), analysis is made on the possibility of sand liquefaction of the subgrade in 15m depth by means of standard penetration tests. The liquefaction indexes are calculated, liquefaction grades are determined and concrete liquefaction control measures are recommended in the paper.