he large deformation occurring during the construction of the inclined shafts of Muzhailing tunnel on LanzhouChongqing railway located in soft ground with high ground stress is presented. Analysis is made on the large deformation on basis of the geological conditions, reinforcement structures, construction process and monitoring data. Effective and reasonable reinforcement measures are proposed in accordance with the site conditions and the theoretical analysis. The technical trend for the subsequent construction of the tunnel in soft ground is provided. The paper can be served as guidance for the subsequent construction of the tunnel and as reference for similar projects in the future.